To: Our Valued Customers

Date: March 17, 2020


In response to the COVID-19 pandemic, the BWH leadership has implemented the shutdown of all research cores; however, the Director of the Brigham Pathology Cores has successfully petitioned for permission to remain open to enable provision of services that support clinical trial-related work only, which will be carried out by a sharply reduced number of personnel. This may lengthen turnaround time but should enable critical clinical trial-related work to get done. We are awaiting additional guidance regarding new Core hours. This page will be updated as soon as this information becomes available.

DF/HCC Pathology Cores Administrative Office:

Effective immediately, all Harvard administrative personnel are required to work offsite. Lauri Wyner, DF/HCC Research Cores Manager will continue to be available via email at as usual.

Specialized histopathology services- longwood, and tissue microarray & imaging:

For non-clinical trial related work, the Cores will stop accepting new work requests on Wednesday the 18th, followed by shutdown of non-clinical trial related work as of 12 p.m., Friday, March 20th. For clinical trial-related work, materials/work requests can be handled as per usual. Please coordinate with and to set a time to pick up your materials [unstained slides, H&Es, scrolls] once you receive notification that your work request is complete. You should practice “social distancing” by limiting your time and interactions when you pick up your materials.

If you have questions regarding existing requests already submitted to the core, or questions on how best to preserve your samples until we are back to “business as usual”, please email

We appreciate your cooperation. As of now, the expectation is that this situation will persist for at least six to eight weeks. I will post regular updates on the Harvard Medical Area Core Management System webpage at

Specialized Histopathology Services Core

Directors: Jon Aster, Anat Stemmer-Rachamimov
BWH Location: 75 Francis Street, Thorn 604, 604B, Boston
MGH Location: Building 149 13th Street, Rm 6122, Charlestown

Core Summary:

The Specialized Histopathology (SHP) Core provides consultative and interpretive pathology 
services including high quality, timely, state-of-the-art analysis of tissues obtained from a 
variety of experimental systems, including rodents, fish, and monkeys. This Core also provides
professional expertise to assist in experimental design and the development and interpretation 
of tests and their results.

Personnel/Contact Information:

Longwood Site

Core Director: Jon Aster, M.D., Ph.D. 
Phone: (617) 278-7483
Fax: (617) 264-5169

MGH Site

Core Co-Director: Anat Stemmer-Rachamimov, M.D.
Phone: (617) 726-5510
Fax: (617) 726-5079

Other Staff:

Longwood Site Lab Manager: Teri Bowman
Phone: (617)-525-9394

MGH Site Lab Manager: Maria Gianatasio
Phone: (617) 726-5510
Email: mgianatasio@mgh.harvard.ed

DF/HCC Pathology Cores Administrative Manager: Lauri Wyner
Phone: (617) 432-4947
Fax: (617) 432-6474


Location of Cores:

The Longwood/BWH facility is located at 75 Frances Street, Thorn, 604, 603b, Boston.
The MGH facility is located at Building 149, 13th Street, Room 6122, Charlestown.


►Tissue trimming, cassetting, processing, and embedding
►Cutting and staining of paraffin-embedded and cryostat sections
►Immunohistochemistry, for both routine and novel markers
►In situ hybridization, using chromogenic methods (Longwood Only)
►Immunofluorescent Staining and access to fluorescence microscope (Training and Unassisted Use)
►All services CAP/CLIA certified (Longwood Only)

Current prices are available on line:

Click on the links provided below to access the Current Core price list:

Specialized Histopathology Services - Longwood

Specialized Histopathology Services - MGH

Getting Started:

To create a new customer account and to request services for an existing account please go to Harvard Medical Area Core Management System

Departmental Web Link: