To advance interdisciplinary health sciences research and innovation by providing high quality bone density and body composition measures to investigators at Mass General Brigham (MGB), and the broader, medical and research community.

Executive Summary:

The MGB Bone Density and Body Composition Research Core uses the latest technology to provide high quality, reproducible measures of bone mineral density (BMD) and body composition by dual energy x-ray absorptiometry (DXA). Dr. Meryl S. LeBoff is the Director of the Bone Density and Body Composition Research Core and has extensive experience in assessing bone density and body composition. She is the Chief of the Calcium and Bone Section and Director of the Skeletal Health and Osteoporosis Center and Bone Density Unit in the Endocrinology, Diabetes and Hypertension Division at BWH, which she founded in 1987. Since that time, it has become a multifaceted program encompassing research and clinical care. She has served on many task forces and advisory boards and committees including the 2013 Expert Panel for the International Society for Clinical Densitometry’s (ISCD) Position Statement on Bone Density and Body Composition Measures. She serves on the Board of Trustees for the National Osteoporosis Foundation. Additionallyshe has research and clinical experience in: new approaches to imaging bone density, structure, and body composition; osteoporosis and other metabolic bone diseases; fracture assessments; evaluation of mineral homeostasis; and bone turnover biomarkers. In a large multi-center study, Dr. LeBoff and her staff at BWH showed the best in vivo and in vitro reproducibility (i.e. precision) among the academic medical centers involved. She and the staff at the Bone Density and Body Composition Research Core have been performing clinical research scans for more than 25 years and are committed to maintaining the highest standards of quality control.

Patient weight limit: 500lb (227kg)


Whole Body BMD and Body Composition
Spine and Hip BMD
Forearm BMD
Vertebral Fracture Assessment (VFA)
Trabecular Bone Score (TBS)
Cross Calibration/ Phantom Scans
Quality Control Data Submission
Infant Whole Body


Horizon W Dual-energy X-ray Absorptiometry (DXA) Scanner, Hologic, Bedford MA
Software version: APEX, S/N: 303895M


221 Longwood Avenue, 2nd Floor Richardson Fuller Building, Boston MA 02115

Getting Started: 

To access the Core, please contact Cindy Yu at 617-732-5643 or by email at cyu@bwh.harvard.edu

Meet our team: