Brigham Research Assay Core

The mission of the BRAC Laboratory is to provide a comprehensive menu of state-of-the-art high-quality research assays to the Partners and non-Partners research communities at competitive costs. The BRAC Laboratory is a dynamic entity seeking to meet the needs of its investigators with new and relevant technologies, and evolving research support. In addition to the immunoassay technology, BRAC offers testing using Equilibrium Dialysis and LC-MS/MS platforms. BRAC's portfolio of LC-MS/MS tests include hormone assays: Testosterone, 25-OH vitamin D2/D3, Estradiol and Estrone, and DHT with additional assays being added in the future as we develop more precise methodology to analyze small molecules, and potentially non-human specimens.

 

Goals:

  • Provide assays in a timely manner at high quality and low cost

  • Offer access to investigators to unique or rare assays

  • Provide the flexibility to add new or previously unavailable assays

  • Offer individualized consulting and experimental assay design

 

BRAC is a CLIA certified laboratory and is accredited by the Joint Commission.


Personnel/contact Information:

Shalender Bhasin, MD
Laboratory Director
Email: sbhasin@partners.org


Facilities:

Location of Core:
221 Longwood Ave
RFB 4th Floor, Rm 477
Boston, MA

FY24 Prices/Menu (Effective 2/01/2024 - 9/30/2024): 

Services 

Internal Fee: Partners 

BC001: Cortisol, Serum

$18.48

BC002: DHEA, Sulfate

$20.80

BC003: Estradiol by Chemiluminescense

$22.53

BC004: FSH

$19.64

BC006: IL‐6

$43.91

BC007: Insulin

$19.64

BC008: LH

$21.95
BC009: Progesterone by Chemiluminescense **

BC011: PTH

$31.20

BC012: SHBG

$30.04
BC014: TSH **

BC016: TPO Antibody

$26.57

BC017: Thyroglobulin Antibody II

$24.26

BC018: Free T3

$20.80

BC019: Free T4

$20.80

BC020: Total T3

$19.64

BC021: Total T4

$19.64
BC022: AMH $50.00
BC023: PSA

 $21.00

EL001: Adiponectin, Total

$47.08

EL005: TNF-alpha

$44.73

EL006: PYY

$51.79

EL007: VCAM

 **

EL008: CTX

$56.50

EL010: ICAM

 **
EL011: N-Telopeptides, Urine **

El012: Osteocalcin

$48.26

EL014: LL‐37

$52.97

EL015: DBP

$44.73

EL016: Ghrelin, Active by ELISA

$49.44

EL017: High Molecular Weight Adiponectin

$47.08

EL019: NTX, Serum

**

EL020: Oxytocin by ELISA

$44.73

EL021: Aldosterone

$28.25
EL021: Inhibin B **

EL024: AER (Aldo Excretion Rate)

$50.61

EL025: Cortisol, Saliva

$35.31

EL028: PRA (Plasma Renin Activity)

$65.40

EL029: ACTH by ELISA

$33.13
EL030: CRP (High Sensitive)
 $34.00
RA007: Cortisol, Urine Free

$38.84

RA009: Active Ghrelin by RIA

 **

RA010: Leptin

$36.49

RA011: P1NP

$48.26

DN001: DNA, Blood

$58.86

DN002: DNA, Cells

$58.86

DN003: DNA, Saliva

$58.86

LC‐MS/MS001: 6-sulphatoxy melatonin (aMT), Urine

 $47.08

LC‐MS/MS002: Cortisol, Serum/Plasma

$32.96

LC‐MS/MS003: Cortisol, Urine

$35.31

LC‐MS/MS004: DHT

$58.86

LC‐MS/MS005: Estradiol/Estrone (E1/E2)

$45.91

LC‐MS/MS006: Estradiol

$42.37

LC‐MS/MS007: Melatonin, Plasma

$35.31

LC‐MS/MS009: Progesterone

$35.31

LC‐MS/MS010: Total Testosterone

$37.67

LC‐MS/MS011: 25OH D2D3

$37.67

LC-MS012: Epinephrine, Urine

 **

LC-MS013: Epinephrine, Plasma

 **

LC‐MS/MS014: Epinephrine/Norepinephrine, Urine combined

$65.92

LC-MS015: Epi/Norepinephrine, Plasma

 **

LC‐MS/MS018: PAH

$55.15

LC‐MS/MS019: Myostatin (GDF‐8)

$58.00

LC‐MS/MS020: GDF‐11

$58.00

LC‐MS/MS021: Angiotensin II

$40.00
LC-MS/MS023: Oxytocin $51.79

LC-MS/MS025: Angiotensin 1-7

$52.32
LC-MS/MS026: Des Arginine bradykinin (DABK)

$47.08
LC-MS/MS027: Des Arginine Kallidin (DAKD)

$47.08
LC-MS/MS028: 11-ketotestosterone
 $34.56
LC-MS/MS029: Allopregnalone

 $44.00
LC-MS/MS030: AVP (Arginine Vasopressin)

 $47.52


CB001: Sex Hormone Combination 

  • SHBG [BC012]
  • Total and Free Testosterone [CB002]
  • DHT [MS004]
  • Estradiol/Estrone [MS005]

$168.00

CB002: Total and Free Testosterone Combo

$74.16

CB003:Myostatin and GDF‐11 Combo

$98.00
CB005: Angiotensin Bradykinin Combo Test
  • Angiotensin II [MS021]
  • Angiotensin 1-7 9[MS025]
  • Des Arginine bradykinin (DABK) [MS026]
  • Des Arginine Kallidin (DADK) [MS027]
 $171.22

***Please Contact the Core for External Pricing, any externally funded testing is subject to Overhead Rates***
The internal user fee was calculated based on the direct costs of providing each service. A Partners investigator using a Partners fund is considered an internal user. The external user fee comprises the direct fee charged to the internal user plus an overhead component. External users are identified as investigators (Partners-affiliated or non-Partners-affiliated) and institutions that use non-Partners funds to pay for research core services. 


**Special Requests 
The indicated tests are also available upon request, but are not part of the standard test menu. There may be additional charges if the kits are not fully used.


Additional Services

Services

Internal Fee: Partners

AD001: Assay Development (per hour)

$372.06

AD002: Assay Validation/Customization (per hour)

$372.06

AD003: DNA Plating

$7.49 per sample or
$250 per 100 samples

Cocktail Preservative Preparation (per tube)

$3.77

Sample Storage (per sample per month)

$0.65


 Getting started:

To Get Started, please contact the core:

BRAC Lab
617-525-9246
Email: BRAC@partners.org


Departmental Web Link:

BRAC Main Core Page:
http://www.brighamandwomens.org/research/brac/default.aspx

CCI Department Page:
http://brighamandwomens.org/research/CCI/default.aspx