Brigham Research Assay Core

The mission of the BRAC Laboratory is to provide a comprehensive menu of state-of-the-art high-quality research assays to the Partners and non-Partners research communities at competitive costs. The BRAC Laboratory is a dynamic entity seeking to meet the needs of its investigators with new and relevant technologies, and evolving research support. In addition to the immunoassay technology, BRAC offers testing using Equilibrium Dialysis and LC-MS/MS platforms. BRAC's portfolio of LC-MS/MS tests include hormone assays: Testosterone, 25-OH vitamin D2/D3, Estradiol and Estrone, and DHT with additional assays being added in the future as we develop more precise methodology to analyze small molecules, and potentially non-human specimens.



  • Provide assays in a timely manner at high quality and low cost

  • Offer access to investigators to unique or rare assays

  • Provide the flexibility to add new or previously unavailable assays

  • Offer individualized consulting and experimental assay design


BRAC is a CLIA certified laboratory and is accredited by the Joint Commission.

Personnel/contact Information:

Shalender Bhasin, MD 
Laboratory Director


Location of Core:
221 Longwood Ave
RFB 4th Floor, Rm 477
Boston, MA

FY19 Prices/Menu (Effective 01/20/2019 - 9/30/2019):


Internal Fee: Partners

BC001: Cortisol, Serum


BC002: DHEA, Sulfate


BC005: Growth Hormone


BC006: IL‐6


BC007: Insulin


BC008: LH


BC011: PTH






CL001: Anti Mullerin Hormone (AMH)


EL001: Adiponectin, Total


EL003: PAI‐1


EL005: TNFa


EL006: PYY


EL008: CTX


EL014: LL‐37


EL015: DBP


EL016: Ghrelin, Active


EL017: Total/High Adiponectin

$34.50 (each fraction)

EL019: NTX, Serum


EL020: Oxytocin


EL021: Aldosterone


EL024: AER (Aldo Excretion Rate)


EL025: Cortisol, Saliva


EL028: PRA (Plasma Renin Activity)


EL029: Active GLP-1


RA009: Ghrelin, Active


RA010: Leptin


RA011: P1NP


DN001: DNA, Blood


DN002: DNA, Cells


DN003: DNA, Saliva


LC‐MS/MS002: Cortisol, Serum/Plasma


LC‐MS/MS003: Cortisol, Urine




LC‐MS/MS005: Estradiol/Estrone (E1/E2)


LC‐MS/MS006: Estradiol


LC‐MS/MS007: Melatonin, Plasma


LC‐MS/MS009: Progesterone


LC‐MS/MS010: Total Testosterone


LC‐MS/MS011: 25OH D2D3


LC‐MS/MS012: Epinephrine, Urine


LC‐MS/MS013: Epinephrine, Plasma


LC‐MS/MS014: Epinephrine/Norepinephrine, Urine combined


LC‐MS/MS015: Epinephrine/Norepinephrine, Plasma combined


LC‐MS/MS016: Norepinephrine, Urine


LC‐MS/MS017: Norepinephrine, Plasma




LC‐MS/MS019: Myostatin (GDF‐8)


LC‐MS/MS020: GDF‐11


CB003:Myostatin and GDF‐11 Combo


LC‐MS/MS021: Angiotensin II


LC‐MS/MS022: Angiotensin III


CB004: Angiotensin II/III Combo


ED001: Free Testosterone by Equilibrium Dialysis


CB001: Sex Hormone Combination (SHBG, Total Testosterone, Free Testosterone, DHT, Estradiol, Estrone)


CB002: Total and Free Testosterone Combo


***Please Contact the Core for External Pricing, any externally funded testing is subject to Overhead Rates***

Special Requests
The following tests are also available upon request, but are not part of the standard test menu. There may be additional charges if the kits are not fully used.

  • BC003: Estradiol
  • BC004: FSH
  • BC009: Progesterone
  • BC010: Prolactin
  • BC013: Testosterone
  • BC014: TSH
  • EL004: Resistin
  • EL007: VCAM
  • EL009: E‐Selectin
  • EL010: ICAM
  • EL011: N‐Telopeptides
  • EL012: Osteocalcin
  • EL013: RBP‐4
  • EL023: Inhibin B
  • EL026: C‐Peptide
  • RA002: ACTH
  • RA007: Cortisol, Urine Free
  • LC‐MS/MS001: 6-sulphatoxy melatonin (aMT), Urine
  • LC‐MS/MS008: 17-Hydroxyprogesterone

Additional Services


Internal Fee: Partners

AD001: Assay Development (per hour)


AD002: Assay Validation/Customization (per hour)


AD003: DNA Plating

$6 per sample or
$225 per 100 samples

Cocktail Preservative Preparation (per tube)


Sample Storage (per sample per month)


PBMC Separation


Getting started:

To Get Started, please contact the core:


Departmental Web Link:

BRAC Main Core Page:

CCI Department Page:

Revised on 2019-01-18 13:11:03 UTC