Psychiatric and Neurodevelopmental Genetics Unit Core Lab

The PNGU Core lab provides a variety of services intended to facilitate the identification and characterization of the genetic basis of psychiatric, behavioral, and neurodevelopment disorders as well as other complex disorders. 

Services include assistance with study design and start-up, custom genotyping (SNP, other), DNA extraction and quantification, and sample preparation, tracking, and storage.

The PNGU core is open to both internal (MGH) and external investigators.

Personnel/Contact Information:

Director: Jordan Smoller, MD, ScD 
Phone: (617) 643-3106 
Email: jsmoller@hms.harvard.edu

Other Staff:

Lab Project Manager: Jonathan Chaponis
Phone: (617) 724-9914
Email: jchaponis@mgh.harvard.edu

Facilities and Equipment:

Location of Core:
Massachusetts General Hospital, Simches Research Building
185 Cambridget Street, 6th Floor
Boston, MA 02114

Major Equipment:
Beckman Coulter NX

Beckman Coulter Multimek

Sequenom MassARRAY System

Tecan (span-4, span-8, 96 well head, PnP arm)

Thermo Scientific Matrix PlateMate 2x2


Services:

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  • Project management, setup, and design
  • DNA extraction, quantification, sample preparation, tracking and storage
  • SNP assay design services
  • SNP genotyping
  • Genetic analysis and bioinformatics services
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Getting Started:

To access the core, please contact Jonathan Chaponis at 617-724-9914 or by email at jchaponis@mgh.harvard.edu


Departmental Web Link:

http://www.massgeneral.org/research/resourcelab.aspx?id=69