The following tables summarize available services, pricing, and deliverables offered by the Gene Editing Core (GEC). Prices are based on standard protocols using human iPSC lines and internal (MGB) funding. Additional charges may apply for non-standard requests or alternate cell types. Non-MGB academic and industry pricing is available upon request.


All gene editing packages include clonal isolation, Sanger sequencing-based genotyping, post-expansion genotyping validation (2 heterozygous and 2 homozygous clones), and mycoplasma testing. Optional genomic analysis services are available upon request.


Gene Editing Services Pricing

Service
MGB Price
Turnaround Time
Delivery
Notes
Small Modification (<50bp)
$9,012
8–12 weeks
2 HETs / 2 HOMs clones (3 cryovials/clone)
Single-nucleotide edits or small indels
Deletion (<60kb)
$10,063
8–12 weeks
2 HETs / 2 HOMs clones (3 cryovials/clone)
Gene knockout or exon deletion
Deletion (>60kb)
$10,671
8–12 weeks
2 HETs / 2 HOMs clones (3 cryovials/clone)
Large deletion or genomic modification (up to 200 kb)
Insertion (>100bp, no selection)
$11,628
12–14 weeks
2 HETs / 2 HOMs clones (3 cryovials/clone)
Gene/Tag knock-in without selection cassette


Genomic Analysis Services Pricing

Service
MGB Price
Turnaround Time
Delivery
Notes
G-band Karyotyping
$784
3–4 weeks
PDF report
Chromosomal integrity assessment
Infinium global diversity array (GDA)
$801
4 weeks
PDF report
Genome-wide SV and LOH detection
Whole Genome Seq
$1,024
4 weeks
Raw data + report
Genome-wide mutation and stability assessment
ddPCR*
$303
1 week
PDF report
Target gene copy number validation

*Price is offered up to 6 samples per target (including positive and negative controls).


iPSC Derivation Services Pricing

Service
MGB Price
Turnaround Time
Delivery
Notes
iPSC derivation from PBMC
$5,987
6–8 weeks
3 clones (3 cryovials/clone)
Requires peripheral blood sample
iPSC derivation from fibroblasts
$6,012
6–8 weeks
3 clones (3 cryovials/clone)
Requires tissue biopsy (e.g., skin)


iPSC Characterization Services Pricing

Service
MGB Price
Turnaround Time
Delivery
Notes
ICC/qPCR for pluripotent markers
$1,013
2 weeks
PDF report
Detects Oct-4, Sox-2, Nanog expression
In vitro trilineage differentiation assay
$1,988
3 weeks
PDF report
Validates differentiation into ectoderm, mesoderm, endoderm
STR identity testing
$200
1 week
PDF report
Confirms iPSC line authenticity
Mycoplasma testing
$98
1 week
PDF report
Detects mycoplasma contamination
G-band Karyotyping
$784
3–4 weeks
PDF report
Chromosomal structural integrity assessment
SNP-Array
$801
4 weeks
PDF report
Genome-wide SV and LOH detection
Whole Genome Sequencing (WGS)
$1,024
4 weeks
PDF report
Genome-wide mutation and integrity profiling



Off-Target Analysis Service Pricing

Service
MGB Price
Turnaround Time
Delivery
Notes
CHANGE-seq analysis
$10,080
3–4 weeks
PDF report
High-sensitivity, genome-wide off-target detection for CRISPR-based DSB editing. Bulk discounts available.