Core Summary
The Genomics and Technology Core (GTC) provides state-of-the-art genomics technologies and expert support to sustain and advance faculty-driven scientific projects at CGM and across MGB. Equipped with specialized personnel and cutting-edge instrumentation, the core enables the development and engineering of genomics libraries for virtually all modern genomics approaches at a sustainable cost. Generate thousands of high-quality libraries annually, using both established sequencing methods (e.g., exome, genome, bulk RNA-seq), and innovating technologies (e.g., single-cell RNA-seq, ATACseq), and custom solutions (e.g., long-insert “jumping” whole-genome, region RNA capture-seq, microRNA-seq, and ribosomal depletion RNA-seq). Our expert team provides comprehensive technical support and bioinformatics guidance to maximize research impact. Led by Dr. Talkowski, with molecular and bioinformatics operations managed by Dr. Celine de Esch and Dr. Serkan Erdin, the GTC is dedicated to advancing scientific discovery.
Contact Information
Primary Contact: Celine De Esch
Email: CGMGTC@mgh.harvard.edu
Phone: 413-404-0836
Location and Hours of Operation
Physical Location: MCPZN5700
Simches Research Building
185 Cambridge St Boston , MA US 02114
Hours of Operation: 9:00 am - 5:00 pm Monday–Friday: 9:00 am - 5:00 pm
Getting Started
To request services or reserve equipment through the GTC, users should submit a service or equipment request by contacting the core directly.
Major Equipment and Capabilities
The GTC maintains major equipment and resources to support its services. Specific equipment names, capabilities, and usage guidelines are available upon request.
External Website
Please visit the Core’s external website for additional information: Talkowski Lab
Last Revised: January 21, 2026
