Dear Core User,

Due to the current situation with COVID-19, per directives from Senior management at Partners and the Hospitals, this research core facilities will have a hiatus in their service offering. We will not be offering service till we are advised to resume operation.

Please stay safe in this challenging time and we look forward to working with you in the future.

The Schepens Eye Research Institute of Mass. Eye and Ear (SERI) Morphology Core provides technical assistance and services for light, confocal, and electron microscopy.  Priority will be given to SERI PI Researchers with NIH-NEI R01 Grants as we are principally funded through a NIH-NEI P30 Core Grant (P30EY003790).   Routine histology sample preparation services include: Routine histological processing, sectioning and staining for frozen, paraffin, methacrylate and epoxy resin tissue preparations.  Complete transmission electron microscopy (TEM) service includes; automated processing of tissue, semi-thin and thin sectioning of cell and tissue samples, TEM imaging and digital image acquisition.  The core facility staff assists with technical problems, procedures, and training on instrumentation inclusive of; Ocular histology & electron microscopy protocols, cryostat sectioning, brightfield, fluorescence, confocal and electron microscopy.  The SERI Morphology Core provides training on two Leica confocal microscopes (SP5 & SP8), Nikon Epifluorescent Microscopes, and a Leica LMD laser microdissection system for SERI Researchers.  For PHS, External PHS Academic, and External Industry Clients please contact us with service requests prior to ordering with PCMS in order to potentially accommodate your needs.