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The Single Cell Genomics Core offers researchers an integrated pipeline to perform successful single cell transcriptomic analyses, including droplet-based single cell transcriptome library preparation, sequencing, and bioinformatic analyses through the core, along with technical expertise on tissue processing, sample preparation, and cell isolation.
The core offers three lines of service to investigators (a) DNA sequencing (b) DNA synthesis and (c) automation of various assays for research purposes.
The core provides DNA extraction from samples provided by the investigators primarily to Heart Center investigators for a low cost fee. However, the core has the capacity to offer services to other investigators, if requested.
The core offers conventional karyotyping and fluorescent in situ hybridization of both human and rodent samples and array based comparative genome hybridization.
The Coreξprovides flexible, high-quality, high-throughput single nucleotide polymorphisms (SNP) genotyping to the research community. Its mission is to provide services to researchers conducting molecular analyses of germline and somatic DNA collected as part of a wide range of investigations into the molecular epidemiology of cancer, including Genome Wide Association Studies (GWAS).
This core provides access to cutting edge genomics technologies and computational biology resources for Partners investigators.
The Mission-Driven Service Core provides custom services for investigators in the Partners community to carry out genetic studies in human disease.
The core houses an Agilent Seahorse XFe24 instrument and provides functional metabolic studies on live tissues and cells.
The aims to establish the impact of genetic variation on the function of the human body. It is also a resource that provides a source of fresh and stored biological samples from healthy human subjects, as well as an electronic atlas that references the expression of genes to the variation found within those genes for research use.