The core offers NGS and Sanger DNA sequencing, fragment analysis, mouse genotyping, and automation of various assays for research purposes.
This core provides access to cutting edge genomics technologies and computational biology resources for MGB investigators.
The core provides the necessary expertise and services to analyze variations in individual genome that translates into medical decisions, practices, interventions tailored to the individual patient (or a small cohort) based on their predicted response or risk of disease.
The MDSC in the Center for Genomic Medicine provides custom services to enable genetic studies in human disease, including processing of blood and skin samples to establish cell lines, DNA and RNA extraction, genotyping and sequencing, and access to Clinical Genetic Research Facility space for subject contact/phenotyping.
The OGI Genomics Core facility was established in April of 2013 by the Massachusetts Eye and Ear Infirmary’s Department of Ophthalmology, with the goal of offering advanced genomics analysis methods and techniques to MEEI’s clinical research staff and affiliates. This investment in instrumentation, infrastructure, and personnel has resulted in a facility capable of performing multiple and varied genomics analyses from experimental design to data analysis and interpretation.
The core houses an Agilent Seahorse XFe24 instrument and provides functional metabolic studies on live tissues and cells.
The aims to establish the impact of genetic variation on the function of the human body. It is also a resource that provides a source of fresh and stored biological samples from healthy human subjects, as well as an electronic atlas that references the expression of genes to the variation found within those genes for research use.
